Preheat oven to 400°F (200°C) and line a baking sheet with parchment paper or lightly grease with olive oil.
In a large mixing bowl, whisk the egg and milk together.
Add the breadcrumbs, parmesan cheese, garlic powder, onion powder, oregano, salt, and pepper to the bowl; stir to combine into a paste.
Add the ground turkey to the mixture and gently fold by hand until just combined, being careful not to overwork the meat.
Scoop approximately 2 tablespoons of the mixture and roll between palms to form 1.5-inch meatballs.
Arrange the meatballs on the prepared baking sheet, spaced 1 inch apart.
Bake for 15 to 20 minutes, or until the internal temperature reaches 165°F (74°C) and the exteriors are lightly browned.
Remove from oven and let rest for 5 minutes before serving.