Cook the high-protein pasta in salted boiling water according to package directions until al dente, drain, and set aside.
In a small bowl, whisk together chili powder, cumin, smoked paprika, garlic powder, onion powder, salt, and black pepper.
Coat the chicken cubes with half of the spice mixture.
Heat 1 tablespoon of olive oil in a large skillet over medium-high heat. Add the chicken and cook for 5-7 minutes until fully cooked through, then remove from the pan.
Add the remaining tablespoon of olive oil to the same skillet. Sauté the bell peppers and onions for 5 minutes until softened and slightly charred.
Reduce the heat to low. Add the chicken broth and the remaining spice mixture, scraping the bottom of the pan to release browned bits.
Whisk in the Greek yogurt until smooth, ensuring the heat is low to prevent curdling.
Fold the cooked pasta and chicken back into the skillet, tossing until thoroughly coated in the sauce.
Garnish with fresh cilantro and serve with lime wedges.