Boil a large pot of salted water and cook high-protein pasta according to package directions until al dente. Drain and set aside.
In a large skillet, heat olive oil over medium-high heat. Add diced onions and bell peppers, sautéing for 5 minutes until softened.
Add the thinly sliced beef to the skillet. Season with salt, pepper, garlic powder, and onion powder. Sear until browned and cooked through, approximately 5 minutes.
In a separate saucepan over low heat, whisk together the milk and Greek yogurt until smooth. Slowly stir in the provolone and mozzarella cheeses until melted and creamy, ensuring the mixture does not reach a boil.
Combine the cooked pasta, the beef and vegetable mixture, and the cheese sauce in the large pot.
Toss everything together over low heat until the sauce coats the pasta evenly and serve immediately.