Preheat oven to 400°F (204°C) and line a baking sheet with parchment paper.
Pat tilapia fillets dry with paper towels, brush with olive oil, and coat both sides thoroughly with blackened seasoning.
Bake tilapia on the prepared sheet for 10 to 12 minutes until the internal temperature reaches 145°F (63°C).
Remove fish from the oven and use a fork to flake the fillets into bite-sized pieces.
On a secondary large sheet pan, arrange tortilla chips in a single, overlapping layer.
Evenly distribute the flaked tilapia, black beans, corn, and jalapeño slices over the chips.
Sprinkle the shredded cheese over the assembled components.
Bake for 5 minutes or until the cheese is melted and bubbling.
Garnish with red onion, diced avocado, and fresh cilantro.
Serve immediately with sour cream and lime wedges on the side.