Place the chicken breasts in the bottom of the slow cooker in a single layer.
In a small bowl, whisk together the salt, black pepper, garlic powder, onion powder, and dried oregano.
Sprinkle the seasoning mixture evenly over both sides of the chicken breasts.
Pour the chicken broth around the sides of the chicken, taking care not to wash the spices off the meat.
Cover the slow cooker and cook on high for 3 to 4 hours or on low for 6 to 8 hours until the chicken is tender and reaches 165°F (74°C).
Transfer the cooked chicken to a large bowl or cutting board.
Using two forks or a hand mixer on the lowest setting, shred the chicken into uniform pieces.
Moisten the shredded chicken with a few tablespoons of the remaining cooking liquid from the slow cooker before serving or storing.